Nephrology
Extreme Early-onset Hypertension Panel
Overview
Test Name
Test Code
Test Category
Test Subcategory
Disease(s) Targeted
Who Is The Test For?
Test Approach
Whole exome sequencing (WES) with in silico gene panel analysis.
No. of Genes
Panel Content
Deliverables
Clinical Report (Download a sample report here)
Turnaround Time
~3-6 weeks*
Specimen Requirements
For detailed information about the sample requirements, please consult our clinical sample requirements page.
About Extreme Early onset hypertension
Extreme Early Onset Hypertension (EEOHT) is severe high blood pressure developing in adulthood, often before age 30, with a strong genetic basis, unlike common essential hypertension which involves complex polygenic factors and lifestyle. Prevalence varies, but these rare, single-gene conditions often involve variants in genes regulating aldosterone and salt balance, such as in Familial Hyperaldosteronism (inherited in an autosomal dominant manner and associated with KCNJ5 gene variants) or Pseudohypoaldosteronism type II (frequently inherited in an autosomal dominant manner and linked to CUL3, KLHL3, WNK1, and WNK4 genes).
Gene Panel Workflow
Order a test using our clinical portal
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