Overview

Test Name

Hereditary Prostate Cancer Panel

Test Code

HCE1011

Test Category

Gene Panels

Test Subcategory

Hereditary Cancer

Disease(s) Targeted

Hereditary Prostate Cancer

Who Is The Test For?

Patients with a family history, clinical suspicion, or diagnosis of hereditary prostate cancer

Test Approach

Whole exome sequencing (WES) with in silico gene panel analysis

No. of Genes

12

Panel Content

ATM, BRCA1, BRCA2, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6, PALB2, PMS2, TP53

Mitochondrial Genome Included In The Analysis

No

Deliverables

Clinical Report (Download a sample report here)

Turnaround Time

~3-6 weeks*

Specimen Requirements

For detailed information about the sample requirements, please consult our clinical sample requirements page.

*Turnaround times are estimated from receipt of satisfactory specimen and test request form at the laboratory to release of clinical report. The turnaround time may vary depending on the nature of the specimen and the complexity of the investigation required. The above table is only a guideline and the complexity of a case and the requirement for further investigations may change this.

About Hereditary Prostate Cancer

Hereditary prostate cancer (HPCa) is cancer caused by gene variants that are passed down from parents to their children. HPCa is often associated with earlier onset of the disease and a higher risk of more aggressive forms compared to non-hereditary prostate cancer. It is estimated to account for 5–15% of all prostate cancer cases. Key genes associated with HPCa include genes associated with DNA repair, such as BRCA1/2,ATM and CHEK2.