Overview

Test Name

Hereditary Lung Cancer Panel

Test Code

HCE1008

Test Category

Gene Panels

Test Subcategory

Hereditary Cancer

Disease(s) Targeted

Hereditary Lung Cancer

Who Is The Test For?

Patients with a family history, clinical suspicion, or diagnosis of Lung Cancer.

Test Approach

Whole exome sequencing (WES) with in silico gene panel analysis

No. of Genes

5

Panel Content

BRCA2, CDKN2A, EGFR, FAM111B, TP53

Mitochondrial Genome Included In The Analysis

No

Deliverables

Clinical Report (Download a sample report here)

Turnaround Time

~3-6 weeks*

Specimen Requirements

For detailed information about the sample requirements, please consult our clinical sample requirements page.

*Turnaround times are estimated from receipt of satisfactory specimen and test request form at the laboratory to release of clinical report. The turnaround time may vary depending on the nature of the specimen and the complexity of the investigation required. The above table is only a guideline and the complexity of a case and the requirement for further investigations may change this.

About Hereditary Lung Cancer

Hereditary lung cancer refers to an inherited genetic predisposition that increases a person's risk of developing lung cancer. While lung cancer is primarily caused by environmental factors like smoking and exposure to carcinogens, inherited genetic predispositions can also play a role. These inherited variants can affect how cells grow and divide, or how the body processes harmful substances. Only a small proportion of lung cancers are linked to inherited variants. Common genes involved can be ones that regulate cell growth, such as EGFR gene, which are also found in somatic mutations in many lung cancers, or genes involved in repairing DNA, such as TP53 gene.