Overview

Test Name

Comprehensive Hereditary Cancer Panel

Test Code

HCE1004

Test Category

Gene Panels

Test Subcategory

Hereditary Cancer

Disease(s) Targeted

Hereditary Cancer

Who Is The Test For?

Patients with a family history, clinical suspicion, or diagnosis of Cancer

Test Approach

Whole exome sequencing (WES) with in silico gene panel analysis

No. of Genes

134

Panel Content

ABRAXAS1, ACD, AIP, AKT1, ALK, APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRAF, BRCA1, BRCA2, BRIP1, CBL, CDC73, CDH1, CDK4, CDKN1B, CDKN2A, CDKN2B, CHEK2, CTC1, CTNNA1, DDB2, DICER1, DKC1, EGFR, EPCAM, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, EXT1, EXT2, FAM111B, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCL, FANCM, FH, FLCN, GREM1, HOXB13, HRAS, KIF1B, KIT, KITLG, KRAS, LZTR1, MAP2K1, MAP2K2, MAX, MBD4, MEN1, MET, MITF, MLH1, MLH3, MRE11, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NF2, NRAS, NTHL1, PALB2, PARN, PDGFRA, PHOX2B, PMS2, POLD1, POLE, POLH, POT1, PPP1CB, PRKAR1A, PRSS1, PTCH1, PTEN, PTPN11, RAD50, RAD51C, RAD51D, RAF1, RB1, RECQL, RET, RIT1, RNF43, RTEL1, SDHA, SDHAF2, SDHB, SDHC, SDHD, SHOC2, SLX4, SMAD4, SMARCA4, SMARCB1, SMARCE1, SOS1, SOS2, SPINK1, SPRED1, STK11, SUFU, TERC, TERF2IP, TERT, TINF2, TMEM127, TP53, TSC1, TSC2, VHL, WRAP53, WRN, WT1, XPA, XPC, XRCC2

Mitochondrial Genome Included In The Analysis

Deliverables

Clinical Report (Download a sample report here)

Turnaround Time

~3-6 weeks*

Specimen Requirements

For detailed information about the sample requirements, please consult our clinical sample requirements page.

*Turnaround times are estimated from receipt of satisfactory specimen and test request form at the laboratory to release of clinical report. The turnaround time may vary depending on the nature of the specimen and the complexity of the investigation required. The above table is only a guideline and the complexity of a case and the requirement for further investigations may change this.