Overview

Test Name

Short QT Syndrome (SQTS) Panel

Test Code

CAE1015

Test Category

Gene Panels

Test Subcategory

Cardiology

Disease(s) Targeted

Short QT Syndrome (SQTS)

Who Is The Test For?

Patients with a family history, clinical suspicion, or diagnosis of Short QT Syndrome (SQTS)

Test Approach

Whole exome sequencing (WES) with in silico gene panel analysis

No. Of Genes

Panel Content

CACNA1C, CACNB2, KCNH2, KCNJ2, KCNQ1, SLC4A3

Mitochondrial Genome Included In The Analysis

Deliverables

Clinical Report (Download a sample report here)

Turnaround Time

~3-6 weeks*

Specimen Requirements

For detailed information about the sample requirements, please consult our clinical sample requirements page.

*Turnaround times are estimated from receipt of satisfactory specimen and test request form at the laboratory to release of clinical report. The turnaround time may vary depending on the nature of the specimen and the complexity of the investigation required. The above table is only a guideline and the complexity of a case and the requirement for further investigations may change this.

About Short QT Syndrome (SQTS)

Short QT syndrome (SQTS) is an inherited cardiac channelopathy characterised by an abnormally short QT interval and increased risk for atrial and ventricular arrhythmias.

Studies suggest a prevalence between 0.02 and 0.1% in adults while in paediatric population the prevalence is 0.05%. Lethal events may occur in both sexes, but a slight male predominance seems to exist.

SQTS is caused by pathogenic variants in the function of ion channels, that are responsible for the currents in the heart.