Overview

Test Name

Hereditary Cancer High Risk Panel

Test Code

HCE1005

Test Category

Gene Panels

Test Subcategory

Hereditary Cancer

Disease(s) Targeted

cancer

Who Is The Test For?

Patients with a family history, clinical suspicion, or diagnosis of cancer.

Test Approach

Whole exome sequencing (WES) with in silico gene panel analysis

No. of Genes

28

Panel Content

APC, ATM, BAP1, BMPR1A, BRCA1, BRCA2, CDH1, CDK4, CDKN2A, CHEK2, EPCAM, MEN1, MLH1, MSH2, MSH6, MUTYH, PALB2, PMS2, POLD1, POLE, PTEN, RAD51C, RAD51D, RET, SMAD4, STK11, TP53, VHL

Mitochondrial Genome Included In The Analysis

No

Deliverables

Clinical Report (Download a sample report here)

Turnaround Time

~3-6 weeks*

Specimen Requirements

For detailed information about the sample requirements, please consult our clinical sample requirements page.

*Turnaround times are estimated from receipt of satisfactory specimen and test request form at the laboratory to release of clinical report. The turnaround time may vary depending on the nature of the specimen and the complexity of the investigation required. The above table is only a guideline and the complexity of a case and the requirement for further investigations may change this.

About cancer

Hereditary breast cancer refers to cancer that is caused by inherited genetic mutations. These mutations significantly increase the risk of developing cancer and can be passed from parents to their children.

These cases are primarily associated with inherited mutations in certain genes that significantly increase an individual's risk of developing cancer.